• CAS#1975145-82-4
  • Namecyclo(RLsKDK)
  • For reserach use only and not for human use!

Product Details

Cost-effective customized wholesale cyclo(RLsKDK) 1975145-82-4

  • Molecular Formula:C31H57N11O9
  • Molecular Weight:727.862

1975145-82-4 Relevant articles

Synthesis and biological evaluation of analogues of the potent ADAM8 inhibitor cyclo(RLsKDK) for the treatment of inflammatory diseases and cancer metastasis

Yim, Victor,Noisier, Ana?s F.M.,Hung, Kuo-yuan,Bartsch, J?rg W.,Schlomann, Uwe,Brimble, Margaret A.

, p. 4032 - 4037 (2016)

The metalloproteinase ADAM8 serves as a ...

1975145-82-4 Process route

C<sub>40</sub>H<sub>73</sub>N<sub>11</sub>O<sub>11</sub>

C40H73N11O11

cyclo(RLsKDK)
1975145-82-4

cyclo(RLsKDK)

Conditions
Conditions Yield
With chlorotriisopropylsilane; trifluoroacetic acid; In water; for 2h;
C<sub>41</sub>H<sub>77</sub>N<sub>11</sub>O<sub>12</sub>

C41H77N11O12

cyclo(RLsKDK)
1975145-82-4

cyclo(RLsKDK)

Conditions
Conditions Yield
Multi-step reaction with 2 steps
1: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide; dichloromethane / 120 h
2: trifluoroacetic acid; chlorotriisopropylsilane / water / 2 h
With chlorotriisopropylsilane; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In dichloromethane; water; N,N-dimethyl-formamide;
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