MF： C43H67N13O14
Radiometal-based radiopharmaceuticals, u...
![[(2S,5R,8S,11S)-8-(4-Amino-butyl)-5-benzyl-11-(3-guanidino-propyl)-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaaza-cyclopentadec-2-yl]-acetic acid](/upload/2025/11/378ce50d-df02-4bf1-ac6e-71aa01558299.png)
[(2S,5R,8S,11S)-8-(4-Amino-butyl)-5-benzyl-11-(3-guanidino-propyl)-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaaza-cyclopentadec-2-yl]-acetic acid
1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid mono(N-hydroxysuccinimidyl ester)
DOTA-cyclo-RGDfK
| Conditions | Yield |
|---|---|
|
With
triethylamine;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 3h;
|
177Lu-lutetium(III) chloride
DOTA-cyclo-RGDfK
177Lu-DOTA-cyclo-RGDfK
| Conditions | Yield |
|---|---|
|
In
aq. acetate buffer;
at 95 ℃;
for 0.5h;
pH=5;
|
[(2S,5R,8S,11S)-8-(4-Amino-butyl)-5-benzyl-11-(3-guanidino-propyl)-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaaza-cyclopentadec-2-yl]-acetic acid
1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid mono(N-hydroxysuccinimidyl ester)
