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  • CAS#57521-78-5
  • NameFederelin
  • For reserach use only and not for human use!

Product Details

MF： C62H81N17O13

Buy high quality and low price Federelin 57521-78-5 now

  • Molecular Formula:C62H81N17O13
  • Molecular Weight:1272.43
  • PKA:9.82±0.15(Predicted) 
  • PSA：472.13000 
  • Density:1.49±0.1 g/cm3(Predicted) 
  • LogP:2.71870 

57521-78-5 Relevant articles

CHYMOTRYPSIN-CATALYZED FRAGMENT COUPLING SYNTHESIS OF D-PHE(6)-GNRH

Schellenberger, V.,Schellenberger, U.,Jakubke, H.-D.,Haensicke, A.,Bienert, M.,Krause, E.

, p. 7305 - 7306 (1990)

p-Glu-His-Trp-OEt and Ser-Tyr-D-Phe-Leu-...

SYNTHESIS AND BIOLOGICAL ACTIVITY OF NOVEL HYDROPHOBIC D-AMINO ACID-6 ANALOGUES OF THE GONADOTROPINRELEASING HORMONE

Erchegyi, Judit,Seproedi, Janos,Vadasz, Zsolt,Nikolics, Karoly,Teplan, Istvan,et al.

, p. 821 - 830 (2007/10/02)

Six new agonistic analogues of GnRH cont...

57521-78-5 Process route

(S)-2-{(S)-3-(1H-Imidazol-4-yl)-2-[((S)-5-oxo-pyrrolidine-2-carbonyl)-amino]-propionylamino}-3-(1H-indol-3-yl)-propionic acid ethyl ester
105823-83-4

(S)-2-{(S)-3-(1H-Imidazol-4-yl)-2-[((S)-5-oxo-pyrrolidine-2-carbonyl)-amino]-propionylamino}-3-(1H-indol-3-yl)-propionic acid ethyl ester

(S)-1-[(S)-2-((S)-2-{(R)-2-[(S)-2-((S)-2-Amino-3-hydroxy-propionylamino)-3-(4-hydroxy-phenyl)-propionylamino]-3-phenyl-propionylamino}-4-methyl-pentanoylamino)-5-guanidino-pentanoyl]-pyrrolidine-2-carboxylic acid carbamoylmethyl-amide
132478-01-4

(S)-1-[(S)-2-((S)-2-{(R)-2-[(S)-2-((S)-2-Amino-3-hydroxy-propionylamino)-3-(4-hydroxy-phenyl)-propionylamino]-3-phenyl-propionylamino}-4-methyl-pentanoylamino)-5-guanidino-pentanoyl]-pyrrolidine-2-carboxylic acid carbamoylmethyl-amide

D-Phe<sup>(6)</sup>-GnRH
57521-78-5

D-Phe(6)-GnRH

Conditions
Conditions Yield
α-chymotrypsin; In N,N-dimethyl-formamide; for 6.5h;
53.2%
D-Cpa<sup>(6)</sup>-GnRH
89624-63-5

D-Cpa(6)-GnRH

D-Phe<sup>(6)</sup>-GnRH
57521-78-5

D-Phe(6)-GnRH

Conditions
Conditions Yield
With potassium hydroxide; hydrogen; Lindlar's catalyst; In N,N-dimethyl-formamide;

57521-78-5 Upstream products

  • 105823-83-4
    105823-83-4

    (S)-2-{(S)-3-(1H-Imidazol-4-yl)-2-[((S)-5-oxo-pyrrolidine-2-carbonyl)-amino]-propionylamino}-3-(1H-indol-3-yl)-propionic acid ethyl ester

  • 132478-01-4
    132478-01-4

    (S)-1-[(S)-2-((S)-2-{(R)-2-[(S)-2-((S)-2-Amino-3-hydroxy-propionylamino)-3-(4-hydroxy-phenyl)-propionylamino]-3-phenyl-propionylamino}-4-methyl-pentanoylamino)-5-guanidino-pentanoyl]-pyrrolidine-2-carboxylic acid carbamoylmethyl-amide

  • 89624-63-5
    89624-63-5

    D-Cpa(6)-GnRH

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